Phentermine vs. Contrave

While the devastating and dangerous problem of obesity spreads more and more every day, it is important to discover existing weight loss medications, their functions, actions and features.

Once a person has a minor case of exceeding weight, a usual weight loss program including low-calorie diet and intense exercising can help. However, patients with the body mass index over 27 need more drastic measures.

Phentermine and Contrave are top effective and popular medications usually prescribed for patients with heavy obesity, accompanied by related health conditions, like:

  • diabetes,
  • uncontrollably high blood pressure,
  • heart problems,
  • high cholesterol and others.

*Despite different active ingredients and other components, Phentermine and Contrave produce approximately the same effect.

Common Features of These Drugs

Powerful weight loss medications are FDA approved prescription obesity treatments that are recommended in instances of severe obesity. Phentermine, as well as Contrave, produces the same potent effect on the vital body functions, thus, stimulating identical positive changes.

Among crucial common features of two medications are precautions, contraindications and drug interactions. Thus, before taking any of these treatments, consult your healthcare provider.

Inform the specialist about all the health problems you have and medications you take. Pay special attention to such conditions as heart problems (history of stroke, heart attack, etc.), high blood pressure, glaucoma and other complications. Do not take any of the drugs if you have used MAO inhibitors within the last 14 days. Mention all the other dietary supplements and pills you take to avoid negative outcomes of wrong drug interaction.


Another important common point about Phentermine and Contrave is that they are more effective in a combination with other weight loss programs. This includes a balanced diet and constant workouts that also improve the results, make them appear faster and be more noticeable.

What’s Different between Phentermine and Contrave?

Apart from a few common features, these two potent weight loss medications have many discrepancies.


Phentermine is an approved medication that changes the work of the central nervous system (both the brain and nerves), increasing the heart rate, blood circulation and other important processes that help suppress the appetite.

Besides, the drug stimulates increased energy production and consumption, so the fat burning process is speeded while lipid digestion is slowed down.

In addition, the medication has a drastic impact on the gastrointestinal tract, significantly improving the metabolism. In general, Phentermine is a time-tested and approved way to treat excess weight.


Contrave is another medication developed to treat obesity.

The main ingredients of the drug are Bupropion and Naltrexone. These powerful components are frequently used as antidepressants, anti-smoking remedies and drugs to cure alcohol abuse.

Apart from these features, the ingredients stimulate the nervous system work faster, suppressing the appetite and boosting the metabolism. Additionally, they help control appetite and modulate eating habits. Due to a different way of affecting the organism, Contrave also causes diverse side effects that are divided into two main sections:

  • Neurological, including insomnia, headaches, high blood pressure, dizziness, anxiety and others;
  • Gastrointestinal, such as upset stomach, dry mouth, nausea, vomiting, diarrhea, etc.