Formation and ways to overcome tolerance to anorexigenic effect of Phentermine
There is a high risk of developing tolerance to anorexigenic effect in long-term use of Phentermine tablets. Tolerance is a state of the body in which therapeutic effect of Phentermine decreases. In other words, the patient ceases to lose weight using this anorectic.
There are several reasons for formation of tolerance to Phentermine anorexigenic effect:
Formation of tolerance to Phentermine anorexigenic effect occurs in several stages:
The first signs of tolerance to Phentermine anorexigenic effect (insomnia, increased appetite) may appear within 2-4 weeks after beginning of obesity treatment.
In daily intake of Phentermine, the anorexic effect gradually weakens, and then completely disappears.
If not to stop taking Phentermine, then tolerance to its anorexigenic effect can develop into the drug dependence over time. That is, the patient will experience a need for use this drug without clinical justification.
Some patients cannot achieve the anorexigenic effect even after the first dose of Phentermine. The presence of tolerance to the anorexigenic effect of Phentermine can be caused by genetic characteristics of the body.
What to do if Phentermine is no longer effective in weight reduction:
- Use another medication to reduce weight
- Use non-drug methods of obesity treatment (diet therapy, physical exercise)
- Consult a healthcare professional involved in drug dependence treatment.