Qsymia contains active substances Topiramate and Phentermine that may cause unwanted side effects.
According to the results of clinical trials, frequent, rare and very rare Qsymia side effects were determined.
- The most common side effects are dry mouth, problems with achieving and maintaining sleep, paraesthesia (burning, numbness or skin tingling), constipation, dysgeusia (taste disorder) or dizziness.
- Rare side effects of Qsymia may include diarrhea, nausea, mood changes, depression, anxiety, limb pain, back pain or fatigue.
- A list of the rarest Qsymia adverse reactions includes chest discomfort, hypokalemia, eye pain, thirst, palpitations, rash, and hair loss.
After Qsymia went on sale, post-marketing studies have been conducted. After that, the list of side effects has been increased and included: tremor, psychosis, increased intraocular pressure and euphoria.
Reports of these adverse reactions were recorded, but not systematized. Therefore, frequency of their occurrence could not be estimated reliably.
Qsymia side effects usually occur in the following situations:
- after using the first dose;
- after increasing a daily dose;
- when exceeding the maximum dose;
- after abrupt cancellation of Qsymia.
If side effects take place, benefit of further obesity treatment should be overestimated. In general, Qsymia adverse events are mild and disappear within a few days after starting obesity treatment.
In case of occurrence of moderate or severe side effects, decrease in a daily dose can be required to alleviate them. If adverse reactions do not disappear and cause discomfort, the doctor may recommend using other medications to treat obesity.