Phentermine/Topiramate is a potent combined medication, which is used for the treatment of overweight and obesity in adults aged 18 years and more. This drug is better known to  consumers under the trademarks “Qsymia” and “Qsiva”.

  • 27 kg/m2 to 29.9 kg/m2 in the presence of such concomitant diseases, as diabetes mellitus or dyslipidemia.If the BMI is 25 kg/m2 to 30 kg/m2, it indicates the presence of excessive weight;
  • 30kg/m2 or higher, regardless of the presence of risk  BMI with this value indicates the presence of obesity of varying severity.

Phentermine/Topiramate should be used in combination with adequate physical loads and low calorie diet. The drug administration in combination with conservative weight loss methods contributes to:

  • decreasein appetite and reduction in food intake;
  • rapidonset of satiety and elimination of

The anti-obesity drug should be taken by one capsule once a day, in the morning, without regard to meals. Treatment of obesity goes in two treatment stages, which last 12 weeks each. After each stage, weight loss results are to be evaluated.

Dose of Phentermine/Topiramate: 3.75 mg/23 mg and 11.25 mg/69 mg – are used for titration and applied no more than 14 days.

  • Initial dose – one 3.75 mg/23 mg capsule once a day for 2 weeks.
  • Maintenance dose – one 7.5 mg/46 mg once daily.

  • Initial dose – one 11.25 mg/69 mg capsule once daily for 2 weeks.
  • Maintenance dose – one 15 mg/92 mg capsule once daily.

Second stage of treatment is initiated only if, patient’s body weight decreased by at least 3% of the initial weight during the first treatment stage. If the weight loss result is less than 3% – Phentermine/Topiramate course is discontinued.

In 12 weeks of the maximum dose use (Phentermine 15 mg/Topiramate 92 mg) the obesity treatment is evaluated. If the patient managed to reduce his weight by at least 5% of the initial body weight, treatment should be continued, otherwise the drug is canceled.Most Phentermine/Topiramate adverse effects are transient and mild. As you continue therapy, they gradually disappear and do not require discontinuation of therapy. Most frequent side effects are headaches, mood and sleep disorders, constipation and dry mouth.

Patients should stop taking the drug and address to a doctor in case they manifest such adverse reactions, like acute myopia, secondary angle closure glaucoma, suicidal thoughts, sustainable increase on the frequency of heart contractions.For patients who are prescribed with or want to start taking Phentermine Topiramate, it’s necessary to find out more about this medication and talk to doctors. Basically, there are certain questions that should be answered:First, Phentermine is a popular and effective appetite suppressant, and its mechanism of action is quite similar to amphetamines. Second, Topiramate is a well-known seizure medication or an anticonvulsant. This combination of meds should be taken together with special diet changes and regular workouts to lose weight faster and safely. For example, those patients who have high cholesterol levels, hypertension or diabetes are often prescribed with Phentermine Topiramate to treat obesity.It’s not allowed to take this medication if you’re pregnant, because its use may result in certain birth defects. The same can be said about patients who are diagnosed with overactive thyroid and glaucoma. Besides, you should avoid taking Phentermine Topiramate with MAO inhibitors because this combination often leads to serious drug interactions.It’s necessary to inform your doctor about other meds that you are taking and medical conditions that you have, including allergic reactions, heart problems, mental ailments, depression, kidney or liver issues, epilepsy, metabolic acidosis, etc. Keep in mind that the intake of Phentermine Topiramate may result in irregular vaginal bleeding, and it’s not approved for patients who are younger than 18 years old.Make sure that you follow all the directions given by your doctor and written on the product label. Only your healthcare provider can determine the right dosage based on important factors, such as your current medical condition. You shouldn’t break, crush or chew Phentermine Topiramate tablets, but make sure that you drink enough water to avoid dehydration during this treatment.As a patient, you need to avoid ketosis diets because they are low in carbs and high in fat. Remember that this medication may impair your reactions and thinking, and don’t drink alcohol to avoid such unwanted side effects as headaches, dizziness, nausea, constipation, vomiting and others.

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