Do you want to lose weight? Looking for effective methods to become slim? Nowadays there are many people, who have the same goal, and it’s possible to choose from a wide range of special pills and supplements, but you need to pick the safest and most effective one. Talk to your doctor about Phentermine 37.5 mg because this medication is perfect for suppressing your appetite and losing weight faster. You should find out more about the main ins and outs involved in this treatment before starting it.
Phentermine Hydrochloride (HCl) 37.5 mg is the maximum effective dose of this drug for weight loss. Today, one of the three dosage forms of Phentermine 37.5 is used to treat obesity: capsules, orally disintegrating or film-coated tablets.
Phentermine 37.5 mg tablets or capsules should be taken no more than once daily. There is a special score line on some Phentermine 37.5 mg diet pills, by which they can be divided into two equal doses of 18.75 mg.
- Tablets with score line can be divided into two parts if only a half of Phentermine 37.5 mg dose is needed.
- After splitting, take the first half of Phentermine 37.5 mg tablet in the morning, and the second after lunch.
- Phentermine 37.5 mg capsules and tablets without score line should be taken as a whole without splitting them.
A dose of 37.5 mg is absolutely equivalent to 30 mg of Phentermine base, which is not used in production of tablets or capsules for weight loss because of low solute potential. However, in the form of hydrochloride – Phentermine rapidly dissolves on the tongue or in the gastrointestinal tract.
- The most popular brand of Phentermine 37.5 mg tablets and capsules is Adipex-P.
- Orally disintegrating tablets are manufactured under the trademark Suprenza.
- In addition, these 375 mg diet pills are produced under the generic name Phentermine HCl.
The manufacturers and / or distributors of Phentermine 37.5 mg are companies such as InvaGen, KVK Tech, Lannett, Mikah Pharma, and Teva.
Uses and Mechanism of Action
Phentermine 3.75 mg is a popular medication prescribed by physicians to help their patients suppress appetite. However, its exact mechanism of action is still unknown, and its intake may act on specific brain areas that are responsible for controlling appetite. Keep in mind that this drug is similar to amphetamine because it works by stimulating your nervous system, increasing a heart rate and boosting blood pressure.
Phentermine 37.5 mg is often prescribed in the right combination with regular exercises and diet changes as a short-term treatment to patients who suffer from obesity. For example, if your body index is higher than 27 kg/m2, this means that its intake is suitable for you. Don’t forget that this body index is associated with certain risk factors for developing heart problems. Make sure that you don’t take Phentermine 37.5 mg with other fat loss products and Fenfluramine, because this combination is related to severe heart issues.
List of Possible Adverse Effects
As all other medications, the intake of Phentermine 37,5 mg may result in experiencing certain side effects, such as vomiting, nausea, dry mouth, unpleasant taste, diarrhea, constipation and others. The good news is that most of them are very rare, mild and pass fast. If you notice any adverse effects related to your central nervous system, including dizziness, insomnia, restlessness, tremor and others, you should talk to your doctor and discuss the possibility to adjust the dose and treatment.
Other Interesting Details
When taking Phentermine 37,5 mg on a long term basis or in high doses, you may end up with either a psychological or physical dependence. The most common withdrawal reactions include fatigue, excessive drowsiness, depression and so on.
It’s necessary to store this weight loss medication in tight containers and at a room temperature to avoid spoilage. What about the right dosage? If you’re prescribed with Phentermine 37.5 mg, you need to take one tablet once a day before your breakfast. Don’t take this drug in the evening because of the increased risk of experiencing insomnia.
Possible Drug Interactions
As you already know, Phentermine 37.5 mg is quite similar to amphetamine, and this means that it can have the same drug interactions. Make sure that you don’t combine it with tricyclic antidepressants, such as Elavil, and MAO inhibitors, like Emsam, because this drug combination will result in hypertension and other serious adverse effects, as your serotonin levels increase.
Most Significant Warnings
For patients who suffer from diabetes, the intake of Phentermine 375 mg may require you to reduce a standard insulin dose. For pregnant and nursing women, it’s advisable to avoid this treatment because of possible side effects. It may develop tolerance, and this is when you need to consult your doctor about the possibility to discontinue the use of Phentermine 37.5 mg. Finally, this medication may affect your ability to engage in potentially dangerous activities, including driving a car or a motorcycle.
A history of Phentermine began more than half a century ago, however until now still considered to be the best drug for weight loss ever sold at pharmacies.
Phentermine has been available for many decades, no wonder that this drug is believed to be one of the most discussed about in the media and on the forums dedicated to obesity issues.
Thousands of real users’ testimonials and diverse information on Phentermine allow obese people to learn about advantages and disadvantages of Phentermine before to start its application.
Unfortunately, Phentermine is contraindicated to many men and women, and they have to use alternative methods for weight loss. However, thousands of men and women create their own weight loss success stories, starting with getting a prescription for Phentermine.
A person with overweight can use Phentermine for weight loss in certain diagnostic criteria. Conditions for prescription for Phentermine pills are different in different countries.
For example, in Australia, Phentermine can be indicated for weight loss to patients with a BMI of 25 and above, in the USA – to patients with a BMI of 27 and above, in New Zealand, Israel, and the UK – to patients with a BMI of 30 and above.
BMI is a body mass index used to classify obesity degree.
- At a BMI from 25 to 29.9, overweight is diagnosed.
- At a BMI of 30 or higher, obesity of Class I, II or III is diagnosed.
To determine correctly BMI, it is important to know the weight in kilograms and height in centimeters. To determine BMI, you can use a special formula, table, or an online-calculator.
Before getting a prescription for Phentermine, not only the BMI has to be calculated but also associated risk factors to be assessed. For this purpose, a comprehensive medical examination is indicated, including but not limited to:
- Blood and urine tests
- Evaluation of thyroid function
A complex medical examination is required to:
- Ensure that conditions for Phentermine indication are present
- Ensure there are no contraindications for Phentermine use
- Choose an optimal dose of Phentermine – taking into account the obesity severity and associated risk factors.
Phentermine efficacy and safety should be assessed and reassessed regularly, at least once every 3 months. Therefore, regardless of the obesity severity and the patient’s age, a prescription for Phentermine is issued maximum for 3 months of continuous medical treatment of obesity.
Film-coated tablets, soft gelatin capsules, or orodispersible tablets Phentermine can be used to fight against obesity.
- Phentermine capsules are characterized by slow sustained-release action, but a very long anorectic effect lasting for the whole day.
- Phentermine pills start working faster than Phentermine capsules, but their anorectic action lasts less than in the capsules.
- Orally dispersible tablets dissolve instantly in the mouth, and their properties are identical (equivalent) to properties of ordinary Phentermine pills.
For manufacture of weight loss pills and capsules, Phentermine is used in the form of Hydrochloride (HCl), or of a complex of ion-exchange resins. Dosage of Phentermine HCL and Phentermine resin is always indicated in milligrams.
Different forms of Phentermine have an equivalent standard specified as the baseline value.
The equivalent dose for Phentermine base 12 mg:
- Phentermine HCl 15 mg
The equivalent doses for Phentermine base 15 mg:
- Phentermine HCl 18.75 mg
- Phentermine resin 75 mg
The equivalent dose for Phentermine base 24 mg
- Phentermine HCl 30 mg
The equivalent doses for Phentermine base 30 mg:
- Phentermine HCl 375 mg
- Phentermine resin 150 mg
Phentermine resin is contained in prolonged-release capsules, and Phentermine Hydrochloride can be contained in both capsules and pills of Phentermine.
The following companies are considered to be among five largest manufacturers of Phentermine pills and capsules in the USA:
- Elite Labs
All these companies specialize in the manufacture of diet pills and capsules, sold at US pharmacies under generic name Phentermine Hydrochloride.
It should be noted that the manufacturers of these diet pills, as well as the companies involved into repackaging and distribution of pharmaceutical products can be indicated as Phentermine suppliers in the USA.
Information about the manufacturer, distributor and (or) repackaging company is always indicated on the label. For example, for Phentermine pills manufactured by Mutual Pharma (a U.S. division of Sun Pharmaceutical, India), the following repackaging companies can be specified:
- A-S Medication Solutions
- Blenheim Pharmacal
- Bryant Ranch Prepack
- Dispensing Solutions
- J. Harkins Company, Inc.
- Keltman Pharmaceuticals Inc.
- Northwind Pharmaceuticals
- PD-Rx Pharmaceuticals, Inc.
- Physicians Total Care
- Proficient Rx LP
- Rebel Distributors Corp
- RxChange Co.
- Stat RX USA LLC
- Unit Dose Services
Some of these companies cooperate with several manufacturers of Phentermine. For example, A-S Medication Solutions owns the US license for repackaging of Phentermine pills manufactured by four pharmaceutical companies: KVK-Tech, Mutual, Teva, and Lannett.
Phentermine pills can be sold at pharmacies under various brand names. For example, Teva brand promotes Phentermine under Adipex-P brand, and Phentermine pills from Akrimax Pharmaceuticals are available in the USA under Suprenza brand.
Several years ago, Ionamin, a Phentermine-containing drug, was very popular in the USA. But currently Ionamin diet pills in the USA are not available anymore (marketing status: Discontinued).
Ionamin pills are withdrawn from the US market, however they are still manufactured, and in 2016, they are still available in the UK. Australia is known to be one of the exporting countries of Ionamin pills. In the United Kingdom, people suffering from overweight can get a prescription for Ionamin (Phentermine) only at clinics specialized in obesity treatment.
Today, Phentermine pills are known under several dozen original names, some of which are popular in several countries.
For example, brand Panbesy is known in Singapore, Thailand, Hong Kong, and South Korea, and brand Duromine is well known in Australia, New Zealand, South Africa, the Philippines, Costa Rica, and Malaysia.
Phentermine pills are available under similar names at the international pharmaceutical market. For example, brand Adipex-P very is popular for Phentermine pills in the USA, and in the Czech Republic – Adipex Retard brand, and South Korea – Adipex brand.
Diet pills Adipex-P, Adipex Retard, and Adipex contain the same active ingredient, but they are manufactured by different companies and have distinctive features.
You can find in our reviews all important information about Adipex and other popular brands of Phentermine.
Nowadays, many people suffer from obesity and relevant health problems. If you are one of them and want to lose weight, then you should read unbiased Phentermine reviews to get more information about this popular medication. Don’t forget to discuss its intake with your doctor because it may have certain side effects and warnings.
What All Patients Should Know
Basically, it’s a generic form of such brand drugs as Adipex and Suprenza used to lose fat by many patients. If you read Phentermine reviews, you’ll understand that it works by suppressing appetite and stimulating your body to burn more calories faster. It’s a controlled substance, and this means that you can take it only for a short period of time, usually no longer than 3 weeks.
Besides, you need to combine the intake of Phentermine with regular workouts and certain nutritional habits to get the most out of it. Keep in mind that this medication is prescribed to those patients who are quite overweight, so doctors often make their final decision based on their body mass index.
Remember that Phentermine works by stimulating your central nervous system and forcing it to produce more neurotransmitters. It was first approved in 1959, and now this medication is available in different forms, including standard pills and capsules.
Basic Warnings and Precautions
You should understand that it’s a habit-forming stimulant, and that’s why it shouldn’t be taken in high doses or on a long-term basis. If you fail to follow the recommendations of your doctor, you risk ending up with dependency, depression, fatigue and other unwanted withdrawals symptoms. Read available Phentermine reviews to learn more about them.
It’s not allowed to take this medication with other weight loss drugs, even herbal supplements. If you have heart problems, atherosclerosis, glaucoma, hypertension, irritability, diabetes and some other health complications, you need to be quite careful when undergoing this weight loss treatment.
Your physician should monitor you closely to avoid severe adverse effects, and you need to stop taking Phentermine as soon as you notice such unwanted symptoms as chest pain, difficulty breathing, swelling and feeling faint.
Remember that this medication may lose its effects if you have been taking it for a while.
What about pregnancy and breastfeeding?
You need to inform your doctor if you’re pregnant or breastfeeding, because you can’t take Phentermine due to possible risks.
Most Common Side Effects
The good news is that they are rare and mild, and you can read more about them in Phentermine reviews of other patients. If you notice any of the following adverse effects, you need to call your physician at once.
They include dry mouth, itching, diarrhea, headache, constipation, vomiting, nausea and others.
Unfortunately, this weight loss treatment may cause more serious adverse effects, including swelling, dizziness, fast heart rate, shaking, hypertension, weakness, chest pain and rash, but they happen only in very rare cases and require immediate medical attention.
In addition, there are some symptoms that indicate quite serious reactions on the intake of Phentermine.
They include unusual tirelessness, upset stomach, thinking problems, insomnia, unusual behaviors, hallucinations, etc. As a patient, you always need to inform your doctor about other medications and supplements that you’re taking to avoid possible drug interactions.
When it comes to Phentermine, you should be careful with MAO inhibitors and some other meds because of serious effects. Don’t drink alcohol during this treatment to avoid negative effects on your central nervous system.