Like other drugs for the treatment of overweight and obesity, Mysimba has certain contraindications to its use.
Relative Mysimba contraindications is a condition of the patient, when, for a certain reason, the use of the drug is possible, yet only under a constant doctor’s supervision.
After a careful assessment of the risk and benefit ratio, the specialist decides on the admissibility of the drug use.
Despite the contraindications, Mysimba may sometimes be prescribed to patients under the age of 18. Particular care requires the use of the drug in elderly patients with moderate hepatic or renal insufficiency.
Controlled hypertension is also not an absolute contraindication to Mysimba use. Caution should be given when centrally acting antihypertensives are taken concurrently with Mysimba.
In cases of relative contraindications, only the attending physician can take the decision on the advisability of Mysimba use.
Both Mysimba and alcohol affect the human central nervous system (CNS). Despite the fact that no clinically significant interaction between Mysimba and alcohol was registered during the trials, the consumption of alcohol-containing drinks should be minimized.
Absolute contraindications are pathological conditions of a person, in which treatment with Mysimba is strictly not recommended because of possible life-threatening situations.
Another absolute contraindication is the patient’s hypersensitivity to the active and inactive ingredients of Mysimba. It is almost impossible to predict in advance whether a person is allergic to Naltrexone or Bupropion.
Therefore, in early treatment with Mysimba, patients are recommended to carefully monitor the response of their body to the drug. If a person experiences face and lips swelling, chest pain, itching, breathing problems, rash, he should discontinue the drug.