Drug Allergy to Phentermine

Just as any other anorectic, Phentermine can affect differently each body. As a rule, most patients do not experience any discomfort or allergic reactions when using this anorectic.

However, there is a small percentage of people in whom Phentermine may cause allergy.

Individual hypersensitivity (intolerance) to anorexigenic substance is a common cause of allergic reactions.

Allergy symptoms to Phentermine may develop rapidly (within a few hours after taking the anorectic) or after a few days.

Administration of even a minimal dose of Phentermine may lead to development of a number of acute allergic reactions, such as:

  1. shortness of breath,
  2. skin rashes,
  3. increased blood pressure.

Drug allergy caused by individual intolerance may manifest by systemic reactions (anaphylactic shock) or reactions of individual organs (rapid heartbeat).

Therefore, if the patient has intolerance to Phentermine or to some other anorexigenic drug, use of these medicines is contraindicated.

The most typical symptoms of drug allergy to Phentermine are skin reactions that manifest in the form of:

  • urticaria,
  • rash,
  • itching.

Mostly, mild allergic skin lesions do not require Phentermine removal, since their intensity decreases, and they disappear by the end of the first weeks of use.

In acute urticaria and itching, use of Phentermine should be discontinued. In severe cases, the patient may require symptomatic treatment of allergic manifestations.

Other reasons for occurrence of drug allergy to Phentermine may include:

  • non-compliance with dosing regimen
  • drug interaction.

According to many experts, use of high doses of Phentermine and non-compliance with the duration of the drug use contribute to development of allergy and side effects.

Desire of many obese people to quickly achieve effective results in weight loss contributes to the fact that they exceed the established doses of Phentermine.

Use of this anorectic in high doses may lead to overdose, accumulation of the drug in the body and development of clearly pronounced allergic reactions.

In these cases, allergic reactions are manifested as:

  • facial swelling
  • frequent sneezing
  • nasal congestion.

In addition, combined use of Phentermine with another anorectic or interaction with drugs used to treat obesity-related diseases can be the cause of drug allergy occurrence.

Clinical studies have shown that there is a high risk of developing drug allergy and poor health in simultaneous use of Phentermine with antidepressants.

It is known that Phentermine may interact with more than 400 different drugs.

Herewith, manifestations of allergic reactions are multiform and expressed in the form of mild urticaria, skin itch, and Quincke’s edema.

To reduce risk of allergic reactions and dangerous interactions, time intervals should be at least 2 hours between intakes of drugs.

However, it should be noted that acute drug allergy to Phentermine develops extremely rare. This anorectic is well tolerated and is completely safe for most people when used in recommended doses.

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